Methylnaltrexone Bromide

Scheme

Rec.INN

ATC (Anatomical Therapeutic Chemical Classification)

A06AH01

CAS registry number (Chemical Abstracts Service)

0073232-52-7

Chemical Formula

C21-H26-Br-N-O4

Molecular Weight

436

Therapeutic Categories

Laxative, treatment of opioid-induced constipation (OIC)

Peripheral acting µ-opioid receptor antagonist

Chemical Names

(17RS)-17-(cyclopropylmethyl)-4,5α-epoxy-3,14-dihydroxy-17-methyl-6-oxo-14beta-morphinanium bromide (WHO)

(17RS)-17-(Cyclopropylmethyl)-4,5α-epoxy-3,14-dihydroxy-17-methyl-6-oxomorphinanium bromide

(5R,9R,13S,14S)-17-Cyclopropylmethyl-3,14-dihydroxy-4,5-epoxymorphinan-6-on-methobromid (IUPAC)

Morphinanium, (17S)-17-(cyclopropylmethyl)-4,5α-epoxy-3,14-dihydroxy-17-methyl-6-oxo-, bromide, (5α)-[USAN]

Foreign Names

• Methylnaltrexonii bromidum (Latin)
• Methylnaltrexon bromid (German)
• Bromure de méthylnaltrexone (French)
• Bromuro de metilnaltrexona (Spanish)

Generic Names

• Methylnaltrexone Bromide (OS: USAN)
• MNTX (IS)
• MOA-728 (IS)
• MRZ 2663 BR (IS)

Brand Names

• Relistor
  Pfizer, Switzerland; Progenics, United States; Wyeth, Austria; Wyeth, Australia; Wyeth, Canada; Wyeth, Germany; Wyeth, Denmark; Wyeth, Spain; Wyeth, Ireland; Wyeth, Netherlands; Wyeth, Norway; Wyeth, Sweden; Wyeth, United States; Wyeth Pharmaceuticals, United Kingdom

International Drug Name Search

Glossary

IUPAC	International Union of Pure and Applied Chemistry
IS	Inofficial Synonym
OS	Official Synonym
Rec.INN	Recommended International Nonproprietary Name (World Health Organization)
USAN	United States Adopted Name
WHO	World Health Organization

Click for further information on drug naming conventions and International Nonproprietary Names.